An in vivo Biomarker to Characterize Ototoxic Compounds and Novel Protective Therapeutics

There are no approved therapeutics for the prevention of hearing loss and vestibular dysfunction from drugs like aminoglycoside antibiotics. While the mechanisms underlying aminoglycoside ototoxicity remain unresolved, there is considerable evidence that aminoglycosides enter inner ear mechanosensor...

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Bibliografske podrobnosti

Principais autores:	Joseph A. Bellairs, Van A. Redila, Patricia Wu, Ling Tong, Alyssa Webster, Julian A. Simon, Edwin W. Rubel, David W. Raible
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2022-07-01
Serija:	Frontiers in Molecular Neuroscience
Teme:	biomarker ototoxicity otoprotection mouse model aminoglycloside hair cell
Online dostop:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.944846/full
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