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Miller–Payne Grading and 70-Gene Signature Are Associated With Prognosis of Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early-Stage Breast Cancer After Neoadjuvant Chemotherapy

IntroductionHR+/HER2− breast cancer (BC) has a much lower pathological complete response (pCR) rate to neoadjuvant chemotherapy (NAC). Therefore, to better stratify the relapse risk for HR+/HER2− non-pCR populations, it is essential to accurate identification new prognostic markers.Materials and Met...

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Principais autores: Liye Wang, Rongzhen Luo, Qianyi Lu, Kuikui Jiang, Ruoxi Hong, Kaping Lee, Ping Zhang, Danyang Zhou, Shusen Wang, Fei Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-09-01
coleção:Frontiers in Oncology
Assuntos:
breast cancer
neoadjuvant chemotherapy
Miller–Payne system
gene expression signature
prognostic
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2021.735670/full
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