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A pan-cancer portrait of PDK1: From oncogenic driver to context-dependent immunological regulator

Summary: Despite being a well-established oncogenic regulator of metabolism promoting aerobic glycolysis, the pan-cancer prognostic value of PDK1, along with its immunomodulatory activity, is still poorly understood. In this research, an integrated multi-omics analysis was used to describe the expre...

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Bibliographic Details
Main Authors: Shuangshuang Duan, Mengmeng Zhang, Miao Sun, Gulinaizaier Abudusaimaiti, Lijun Zhang, Huibin Liu
Format: Artigo
Language:Inglês
Published: Elsevier 2026-01-01
Series:Cancer Treatment and Research Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468294226000717
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