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Improved prediction of anti-angiogenic peptides based on machine learning models and comprehensive features from peptide sequences

Abstract Angiogenesis is a key process for the proliferation and metastatic spread of cancer cells. Anti-angiogenic peptides (AAPs), with the capability of inhibiting angiogenesis, are promising candidates in cancer treatment. We propose AAPL, a sequence-based predictor to identify AAPs with machine...

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Autori principali: Yun-Chen Lee, Jen-Chieh Yu, Kuan Ni, Yu-Chuan Lin, Ching-Tai Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-06-01
Serie:Scientific Reports
Accesso online:https://doi.org/10.1038/s41598-024-65062-9
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