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Trimethylamine N-Oxide (TMAO) Inducing Endothelial Injury: UPLC-MS/MS-Based Quantification and the Activation of Cathepsin B-Mediated NLRP3 Inflammasome

TMAO is a new risk biomarker for cardiovascular disease. With trimethylammonium as its main chemical skeleton, TMAO is structurally similar to many endogenous metabolites, such as acetylcholine, carnitine, phosphorylcholine, etc. The mechanism of TMAO on the pathological process of CVD is still uncl...

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Principais autores: Dongyu Lei, Wenbo Yu, Yi Liu, Yujie Jiang, Xiaohui Li, Jing Lv, Ying Li
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-04-01
Series:Molecules
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Acceso en liña:https://www.mdpi.com/1420-3049/28/9/3817
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