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The Loss of Masculine With Declined Serum DHT Is Associated With High Risk of Hepatocellular Carcinoma in Chinese Men

Background: Hepatocellular carcinoma (HCC) is a male-predominant cancer. However, the relationship between 5α-dihydrotestosterone (DHT), the active form of testosterone, and HCC risk has not been established yet.Methods: We performed a serum epidemiological study in the Chinese population. From 2010...

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Main Authors: Lichun Wang, Azhar Rasul, Zili Liu, Ying Pan, Weihua Wang, Jiang Li, Xiaomeng Li
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Endocrinology
Subjects:
hepatocellular carcinoma (HCC)
dihydrotestosterone
estradiol
liver function
liver injury
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00362/full
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