Chemoselective reactions of electrophiles with quinazoline amides; 3-alkylquinazoline-2,4-(1H,3H)-diones, and 2-arylquinazoline-4(3H)ones and their thioamide regioisomers

The study draws a solid theoretical basis governing the reaction of amides and thioamides with electrophiles to give either N, O or S- substitutions. This study was carried out on the model compounds quinazoline amides; 3-alkylquinazoline-2,4-(1H,3H)-diones and 2-arylquinazoline-4(3H)ones and their...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	mohamed Abd El-Moneim, mohammed megahed, Ibrahim ali, walid fathalla
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Port Said University, Faculty of Sciences 2025-10-01
Schriftenreihe:	Alfarama Journal of Basic & Applied Sciences
Schlagworte:	soft electrophile hard electrophile ambident nucleophile HSAB Principle computational analysis
Online-Zugang:	https://ajbas.journals.ekb.eg/article_445392_3884bcc90918c473cfc579668dd8213f.pdf
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