Spectral cytometry of rheumatoid arthritis patients implicates myeloid dendritic cells and granular HLA-DR+CD15+CD16+ cells in pro-inflammatory antigen presentation

IntroductionRheumatoid arthritis (RA) is a systemic autoimmune disease that leads to inflammation of synovial joints and other organs. Many RA patients “share” a common peptide sequence within the HLA-DR (MHC II) molecule expressed on antigen-presenting cells (APC), suggesting that HLA-DR+ cells are...

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Autors principals:	Christian Geier, Haani Qudsi, Estelle Khairallah, Jihad Ben Gabr, Robert Winchester, Andras Perl
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-07-01
Col·lecció:	Frontiers in Immunology
Matèries:	rheumatoid arthritis CD1c+ dendritic cells intermediate monocytes myeloid cells low-density granulocytes antigen-presenting cell
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1596609/full
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