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Sequential PD-1 inhibitors as consolidative therapy post-CD19 CART in relapsed/refractory NHL: a propensity score matching cohort study

Abstract Background CD19-directed chimeric antigen receptor T-cell therapy (CART) has improved outcomes for relapsed/refractory non-Hodgkin lymphoma (R/R NHL). However, patients with high-risk molecular features, such as double-expressor lymphoma (DEL+), characterized by concurrent MYC and BCL-2 pro...

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Principais autores: Bin Xue, Jie Zhou, Xi Chen, Yifan Liu, Huina Lu, Zeyu Zhu, Wenjun Zhang, Li Zhang, Aibin Liang, Ping Li, Xiu Luo
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:Journal of Translational Medicine
Fag:
CD19
CART/CAR-T
PD-1 inhibitors
NHL
PSM
Online adgang:https://doi.org/10.1186/s12967-025-07281-w
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