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Engagement of chymase-positive mast cells in myocardial damage associated with COVID-19

BackgroundAcute myocardial injury is a frequent and severe complication of COVID-19, contributing to increased mortality. This study investigates the role of chymase-positive mast cells (MCs) in myocardial damage among patients who died from severe or critical COVID-19.MethodsCardiac tissue samples...

Celý popis

Uloženo v:
Hlavní autoři: Andrey V. Budnevsky, Sergey N. Avdeev, Ekaterina D. Arkhipova, Djuro Kosanovic, Viktoria V. Shishkina, Tatiana A. Chernik, Evgeniy S. Ovsyannikov, Inna M. Perveeva, Andrey A. Filin, Roman E. Tokmachev, Alexander V. Pertsev, Elena E. Ivanova, Tatiana V. Samoylenko, Lyubov N. Antakova
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-05-01
Edice:Frontiers in Cardiovascular Medicine
Témata:
acute myocardial injury
cardiac fibrosis
chymase
COVID-19
mast cells
On-line přístup:https://www.frontiersin.org/articles/10.3389/fcvm.2026.1816510/full
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