Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease.
Injury to the glomerular podocyte is a key mechanism in human glomerular disease and podocyte repair is an important therapeutic target. In Fabry disease, podocyte injury is caused by the intracellular accumulation of globotriaosylceramide. This study identifies in the human podocyte three endocytic...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science (PLoS)
2011-01-01
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| Reeks: | PLoS ONE |
| Online toegang: | https://doi.org/10.1371/journal.pone.0025065 |
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