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RANK Signaling Amplifies WNT-Responsive Mammary Progenitors through R-SPONDIN1

Systemic and local signals must be integrated by mammary stem and progenitor cells to regulate their cyclic growth and turnover in the adult gland. Here, we show RANK-positive luminal progenitors exhibiting WNT pathway activation are selectively expanded in the human breast during the progesterone-h...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Purna A. Joshi, Paul D. Waterhouse, Nagarajan Kannan, Swami Narala, Hui Fang, Marco A. Di Grappa, Hartland W. Jackson, Josef M. Penninger, Connie Eaves, Rama Khokha
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2015-07-01
Rangatū:Stem Cell Reports
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2213671115001551
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