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Radical defluoroallylation of polyfluoroalkyl compounds with alkenes via synergistic photoredox/cobalt catalysis

Abstract Selective functionalization and high-value conversion of polyfluoroalkyl compounds is of paramount importance due to their widespread use in pharmaceuticals, agrochemicals, and advanced materials. However, the formidable stability of C(sp3)–F bonds, exacerbated by strong electron-withdrawin...

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Principais autores: Demin Ren, Shuang Deng, Yatao Wang, Wei Ding, Pengjie Wang, Jia Yan, Shengchun Wang, Jiaxin Yuan, Baoquan Wan, Xiaotian Qi, Aiwen Lei, Hong Yi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2026-02-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-026-68840-3
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