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Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR

Background/Aims: Cystic fibrosis (CF) is a lethal recessive disorder caused by mutations in the CF transmembrane conductance regulator (CFTR). ΔF508, the most common mutation, is a misfolded protein that is retained in the endoplasmic reticulum and degraded, precluding delivery to the cell surface [...

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Huvudupphov: Inna Sabirzhanova, Clément Boinot, William B. Guggino, Liudmila Cebotaru
Materialtyp: Artigo
Språk:Inglês
Utgiven: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Serie:Cellular Physiology and Biochemistry
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Länkar:https://www.karger.com/Article/FullText/495596
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