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Talaporfin Sodium as a Clinically Translatable Radiosensitizer in Radiodynamic Therapy

Talaporfin sodium (mono-L-aspartyl chlorin e6; NPe6), a second-generation photosensitizer, is clinically used in photodynamic therapy (PDT). It accumulates preferentially in tumors and exhibits deep tissue penetration, rapid systemic clearance, and minimal photosensitivity. However, treatment of dee...

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Principais autores: Junko Takahashi, Junkoh Yamamoto, Kohei Suzuki, Shohei Nagasaka, Kaizhen Yang, Haobo Zhao, Teppei Yamaoka
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-12-01
Serier:Biomolecules
Fag:
radiodynamic therapy (RDT)
radiotherapy
photodynamic therapy (PDT)
talaporfin sodium
mono-L-aspartyl chlorin e6 (NPe6)
pancreatic cancer
Online adgang:https://www.mdpi.com/2218-273X/15/12/1748
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