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Synthesis, Molecular Docking Studies, In Vitro Antimicrobial and Antifungal Activities of Novel Dipeptide Derivatives Based on N-(2-(2-Hydrazinyl-2-oxoethylamino)-2-oxoethyl)-Nicotinamide

A series of linear dipeptide derivatives (4–10) were prepared and evaluated as antimicrobial agents via the synthesis of N-(2-(2-hydrazinyl-2-oxoethylamino)-2-oxoethyl) nicotinamide (4). Compound 4 was reacted with 4-chlorobenzaldehyde or 4-hydroxybenzaldehyde, to give the hydrazones 5 and 6, respec...

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Autors principals: Gaber Moustafa, Hemat Khalaf, Ahmed Naglah, Asma Al-Wasidi, Nawal Al-Jafshar, Hassan Awad
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2018-03-01
Col·lecció:Molecules
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Accés en línia:http://www.mdpi.com/1420-3049/23/4/761
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