FRET prioritization score to choose high-quality hit equity and reduce the impact of interference by quenching and fluorescence

Förster resonance energy transfer (FRET) proximity assays are commonly used in hit discovery for investigating protein-protein interactions, protein modification, molecular glues and small analytes like cyclicAMP or GDP. While they are thought to be robust to artefacts, analyzing their output solely...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Antonia Turberville, Tiziana Monteverde, Syedah Neha Ashraf, Delyan Ivanov
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-08-01
coleção:	SLAS Discovery
Assuntos:	FRET Fluorescence polarisation Hit discovery Prioritization Utility score
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2472555226000146
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!