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Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance.

microRNAs (miRNAs) are small non-coding RNAs that regulate mRNA stability and translation through the action of the RNAi-induced silencing complex (RISC). Our current understanding of miRNA function is inferred largely from studies of the effects of miRNAs on steady-state mRNA levels and from seed m...

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Autors principals: David G Hendrickson, Daniel J Hogan, Daniel Herschlag, James E Ferrell, Patrick O Brown
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2008-05-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC2330160?pdf=render
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