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Epac1 Blocks NLRP3 Inflammasome to Reduce IL-1β in Retinal Endothelial Cells and Mouse Retinal Vasculature

Inflammation is an important component of diabetic retinal damage. We previously reported that a novel β-adrenergic receptor agonist, Compound 49b, reduced Toll-like receptor 4 (TLR4) signaling in retinal endothelial cells (REC) grown in high glucose. Others reported that TLR4 activates high-mobilit...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Youde Jiang, Li Liu, Elizabeth Curtiss, Jena J. Steinle
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Wiley 2017-01-01
Saila:Mediators of Inflammation
Sarrera elektronikoa:http://dx.doi.org/10.1155/2017/2860956
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