HMGB1/NF-κB Axis, IL-8, and Cuproptosis Contribute to Cisplatin-Induced Testicular Injury: Protective Potential Effect of Thymol

Background: Cisplatin (CP) use is associated with testicular toxicity. Cuproptosis-related genes are associated with dysfunctional spermatogenesis. Additionally, the HMGB1/NF-κB axis has been involved in cuproptosis-mediated inflammation. The aim of the current study was to investigate the effect of...

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Hlavní autoři:	Layla Alkharashi, Iman Hasan, Aliyah Almomen, Qamraa H. Alqahtani, Yasmen F. Mahran, Amul M. Badr, Reem T. Atawia, Awatif Binmughram, Rehab Ali, Nadrah Alamri, Amira M. Badr
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2025-11-01
Edice:	Biomolecules
Témata:	cisplatin testes HMGB1 cuproptosis IL-8 thymol
On-line přístup:	https://www.mdpi.com/2218-273X/15/11/1595
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