CagA Effector Protein in <i>Helicobacter pylori</i>-Infected Human Gastric Epithelium in Vivo: From Bacterial Core and Adhesion/Injection Clusters to Host Cell Proteasome-Rich Cytosol

A key role in the carcinogenic action of <i>Helicobacter pylori</i> is played by the effector protein CagA, the first identified oncoprotein of the bacterial world. However, the present knowledge in regard to the bacterial injection of CagA into epithelial cells (through a type IV secretion system)...

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Hlavní autoři:	Vittorio Necchi, Vittorio Ricci, Patrizia Sommi, Enrico Solcia
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2019-10-01
Edice:	Toxins
Témata:	<i>helicobacter pylori</i> caga human gastric epithelium in vivo host–pathogen interactions gastric cancer ultrastructural immunocytochemistry
On-line přístup:	https://www.mdpi.com/2072-6651/11/11/618
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