Disruption of Bile Acid Metabolism in the Gut–Liver Axis Predisposes Mice to Inflammatory Bowel Disease

ABSTRACT Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease that is frequently associated with inflammatory bowel disease (IBD). However, the precise mechanisms linking these conditions remain unclear. In this study, we established a murine model of experimental sclerosing c...

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Bibliografische Detailangaben

Hauptverfasser:	Hui Chang, Yang Jiang, Qiong Zhao, Zhen Su, Mingyang Chen, Qiufen He, Jingbo Lai, Yingru Jiang, Jing Zheng, Ruolang Pan, Jianzhong Shao, Robert Chunhua Zhao, Ye Chen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2025-10-01
Schriftenreihe:	MedComm
Schlagworte:	primary sclerosing cholangitis bile acid gut–liver axis immune cell homeostasis susceptibility to IBD
Online-Zugang:	https://doi.org/10.1002/mco2.70429
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