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HMGCR genetic variation and risk of new-onset type 2 diabetes in statin users

Abstract Background Statins are widely prescribed lipid-lowering agents, but their use is associated with an increased risk of new-onset type 2 diabetes mellitus (NO-T2DM) ranging from 9% to 13%. While genetic variants in 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), the pharmacological target o...

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Hlavní autoři: Areej S. Albawa’neh, Mais N. Alqasrawi, Zeina N. Al-Mahayri, Nour al dain Marzouka, Lilas Dabaghie, Dana Hamza, Lubna Q. Khasawneh, Virendra Misra, Husam Ouda, Bassam R. Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2026-04-01
Edice:Human Genomics
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On-line přístup:https://doi.org/10.1186/s40246-026-00962-7
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