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Surfactant Protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model

<p>Abstract</p> <p>Background</p> <p>Allergen-containing subpollen particles (SPP) are released from whole plant pollen upon contact with water or even high humidity. Because of their size SPP can preferentially reach the lower airways where they come into contact with surfactant protein (SP)-D. The...

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Main Authors: Schleh Carsten, Rothen-Rutishauser Barbara M, Blank Fabian, Lauenstein Hans D, Nassimi Matthias, Krug Norbert, Braun Armin, Erpenbeck Veit J, Gehr Peter, Hohlfeld Jens M
Format: Artigo
Language:Inglês
Published: BMC 2012-02-01
Series:Respiratory Research
Subjects:
Allergen Particle
Subpollen Particles
SPP
Surfactant Protein D
SP-D
Cytokines
Online Access:http://respiratory-research.com/content/13/1/8
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