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Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes

Abstract Background Epidermal growth factor receptor inhibitors (EGFRIs) are used to treat certain cancers but frequently cause cutaneous inflammation that can hinder treatment. This is due in part to the effects of EGFRIs on pro-inflammatory signaling by interferon-γ (IFN-γ). However, the impact of...

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Autors principals: David C. Gibbs, Myles R. McCrary, Carlos S. Moreno, Lindsey Seldin, Chaoran Li, Nourine A. H. Kamili, Brian P. Pollack
Format: Artigo
Idioma:Inglês
Publicat: BMC 2025-02-01
Col·lecció:BMC Genomics
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Accés en línia:https://doi.org/10.1186/s12864-025-11237-1
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