Dantrolene improves left ventricular diastolic property in mineralcorticoid-salt-induced hypertensive rats

Left ventricular (LV) diastolic dysfunction is increasingly common in heart failure with preserved ejection fraction (HFpEF), and new drug therapy is desired. We recently reported that dantrolene (DAN) attenuates pressure-overload induced hypertrophic signaling through stabilization of tetrameric st...

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Autors principals:	Junya Nawata, Takeshi Yamamoto, Shinji Tanaka, Yasutake Yano, Tomoyuki Uchida, Shohei Fujii, Yoshihide Nakamura, Takeshi Suetomi, Hitoshi Uchinoumi, Tetsuro Oda, Shigeki Kobayashi, Masafumi Yano
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-07-01
Col·lecció:	Biochemistry and Biophysics Reports
Matèries:	Dantrolene Calmodulin Hypertrophy HFpEF
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2405580823000304
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