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The nonenzymatic template-directed ligation of oligonucleotides

The nonenzymatic template-directed ligation of oligonucleotides containing 2', 3'-cyclic phosphate was investigated in the presence of divalent cations. Ligation of the oligonucleotides readily occurred in the presence of Mg<sup>2+</sup>, Mn<sup>2+</sup>, Co<sup>2+</sup>, Zn<sup>2+</sup>, Pb<sup>2+<...

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Autori principali: A. V. Lutay, E. L. Chernolovskaya, M. A. Zenkova, V. V. Vlassov
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copernicus Publications 2006-01-01
Serie:Biogeosciences
Accesso online:http://www.biogeosciences.net/3/243/2006/bg-3-243-2006.pdf
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