A phase 1b clinical trial to determine the safety, tolerability and immunogenicity of simian adenovirus and poxvirus vectored vaccines against Mycobacterium avium complex subspecies in patients with active Crohn’s diseaseResearch in context

Summary: Background: Crohn’s Disease (CD) is a chronic, debilitating condition hypothesised to be associated with Mycobacterium avium ssp paratuberculosis (MAP) infection. It is the causative pathogen of the granulomatous inflammatory enteritis in ruminants, Johne’s Disease. A developing treatment...

Description complète

Détails bibliographiques

Auteurs principaux:	Jeremy Sanderson, Jeremy Aboagye, Rebecca Makinson, Katerina Rapi, Samuel Provstgaard-Morys, Lisa Stockdale, Alison Lawrie, Isabelle Lanigan, Nishat Halim, Abdel Douiri, Emily Greenlay, Rayka Malek, Emma Gray, Lindsey West, Fatima El Oulidi, Paul Ian Cross, Michael Stallibrass, Sarah C. Gilbert, Adrian V.S. Hill, Katie J. Ewer
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2025-03-01
Collection:	EBioMedicine
Sujets:	Viral vectored vaccines Mycobacterium avium ssp paratuberculosis Crohn’s disease Johne’s disease
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2352396425000143
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!