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The interconnected roles of TRIM21/Ro52 in systemic lupus erythematosus, primary Sjögren’s syndrome, cancers, and cancer metabolism

Abstract Protein tripartite motif-containing 21 (TRIM21/Ro52), an E3 ubiquitin ligase, is an essential regulator of innate immunity, and its dysregulation is closely associated with the development of autoimmune diseases, predominantly systemic lupus erythematosus (SLE) and primary Sjögren’s syndrom...

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Bibliografiske detaljer
Principais autores: Chueh-Hsuan Hsu, Yung-Luen Yu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-11-01
Serier:Cancer Cell International
Fag:
Online adgang:https://doi.org/10.1186/s12935-023-03143-x
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