Analysis of DNA mismatch repair and microsatellite instability in molecular typing of endometrial carcinoma

Abstract DNA mismatch repair (MMR)/microsatellite instability (MSI) status is an indispensable biomarker for predicting immunotherapy response, screening for Lynch syndrome (LS), and molecularly classifying endometrial carcinoma (EC). To investigate the consistency and the causes of discordance amon...

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Bibliographic Details

Main Authors:	Na-Mei Li, Hai-Peng Cheng, Peng Zhou, Xiao-Hong Li
Format:	Artigo
Language:	Inglês
Published:	Springer 2026-02-01
Series:	Discover Oncology
Subjects:	Endometrial carcinoma (EC) DNA mismatch repair Microsatellite instability Next generation sequencing MLH1 promoter methylation
Online Access:	https://doi.org/10.1007/s12672-026-04566-4
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