Parecoxib sodium alleviates ischemia reperfusion‐induced pulmonary injury via inhibiting ERK/NF‐κB and further activating the HIF‐1α pathway

Abstract Introduction The lungs are extremely vulnerable to ischemia/reperfusion (I/R), which is characterized by intense inflammation, oxidative stress, alveolar damage, and vascular permeability. Parecoxib sodium (Pare) has been shown to exert protective effects against multiple I/R‐induced tissue...

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Detalhes bibliográficos

Principais autores:	Jiantao Guo, Yiping Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2022-09-01
coleção:	Immunity, Inflammation and Disease
Assuntos:	hypoxia‐inducible factor‐1α inflammatory response ischemia reperfusion oxidative stress parecoxib
Acesso em linha:	https://doi.org/10.1002/iid3.684
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