Genotoxic Effects of Cylindrospermopsin, Microcystin-LR and Their Binary Mixture in Human Hepatocellular Carcinoma (HepG2) Cell Line

Simultaneous occurrence of cylindrospermopsin (CYN) and microcystin-LR (MCLR) has been reported in the aquatic environment and thus human exposure to such mixtures is possible. As data on the combined effects of CYN/MCLR are scarce, we aimed to investigate the adverse effects related to genotoxic ac...

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Autori principali:	Leticia Díez-Quijada, Klara Hercog, Martina Štampar, Metka Filipič, Ana M. Cameán, Ángeles Jos, Bojana Žegura
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2020-12-01
Serie:	Toxins
Soggetti:	DNA double-strand breaks cell-cycle mRNA expression microcystin-LR cylindrospermopsin mixture
Accesso online:	https://www.mdpi.com/2072-6651/12/12/778
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