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Adoptive transfer of regulatory T cells in pediatric patients with treatment-refractory acute graft-versus-host disease

Abstract: Despite advancements in donor selection, conditioning regimens, and immunosuppressive therapies, graft-versus-host disease (GVHD) remains a frequent complication of allogeneic hematopoietic stem cell transplantation (HSCT). Regulatory T cells (Tregs), key mediators of immune tolerance, hav...

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Bibliografiske detaljer
Principais autores: Ariana de Oliveira Mekonnen, Britta Lamottke, Sybille Landwehr-Kenzel, Sabine Tischer-Zimmermann, Agnes Bonifacius, Astrid Wintering, Rebecca Schultze-Florey, Fatih Noyan, Lubomir Arseniev, Lilia Goudeva, Krasimira Aleksandrova, Christoph Priesner, Karl-Walter Sykora, Doris Franke, Imeke Goldschmidt, Rita Beier, Matthias Edinger, Britta Eiz-Vesper, Martin G. Sauer, Britta Maecker-Kolhoff
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-06-01
Serier:Blood Immunology & Cellular Therapy
Online adgang:http://www.sciencedirect.com/science/article/pii/S3050597626000096
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