Synthesis and in silico study of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives as suitable therapeutic agents

Abstract In the study presented here, a new series of 2-furyl(4-{4-[(substituted)sulfonyl]benzyl}-1-piperazinyl)methanone derivatives was targeted. The synthesis was initiated by the treatment of different secondary amines (1a-h) with 4-bromomethylbenzenesulfonyl chloride (2) to obtain various 1-{[4...

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Detalles Bibliográficos

Principais autores:	Ghulam Hussain, Muhammad Athar Abbasi, Aziz-ur-Rehman, Sabahat Zahra Siddiqui, Syed Adnan Ali Shah, Muhammad Ashraf, Qurat-ul-Ain, Irshad Ahmad, Rabia Malik, Muhammad Arif Lodhi, Farman Ali Khan, Muhammad Shahid, Hina Fatima
Formato:	Artigo
Idioma:	Inglês
Publicado:	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2017-04-01
Series:	Brazilian Journal of Pharmaceutical Sciences
Assuntos:	Piperazine derivatives/antimicrobial activity Piperazine derivatives/in silico Piperazine derivatives/Cholinesterase assays Piperazine derivatives/ hemolytic activity.
Acceso en liña:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000100613&lng=en&tlng=en
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