DNASE1L3 functions as a significant metastatic suppressor by attenuating MYH9/β-catenin/c-Jun/LncRNA-KDM4A-induced E-cadherin ubiquitination degradation in nasopharyngeal carcinoma

Abstract Background Deoxyribonuclease 1 Like 3 (DNASE1L3) is a member of the deoxyribonuclease I family that is associated with some diseases, including systemic lupus erythematosus and hypocomplementemic urticarial vasculitis. Recently, abnormal DNASE1L3 was preliminarily shown to correlate with tu...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Xingyu Tao, Xiong Liu, Xiangdong Zhao, Beixian Zhou, Chao Cheng, Weiwei Yan, Jingjing He, Haolin Cao, Yun Su, Jianyang Xin, Xiaoning Gan, Hong Peng, Wanli Lin, Weiyi Fang, Zhen Liu
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2026-05-01
سلاسل:	Cellular & Molecular Biology Letters
الموضوعات:	DNASE1L3 Epithelial-mesenchymal transition Metastasis suppression MYH9/β-catenin/c-Jun/LncRNA-KDM4A axis Nasopharyngeal carcinoma
الوصول للمادة أونلاين:	https://doi.org/10.1186/s11658-026-00911-1
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!