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CRP/anti-CRP antibodies assembly on the surfaces of cell remnants switches their phagocytic clearance towards inflammation

Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disease characteris¬ed by the production of autoantibodies, formation of immune complexes (IC), and activation of complement that ultimately fuel acute and/or chronic inflammation. Accumulation in blood and tissues of post-apoptotic r...

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Kaydedildi:
Asıl Yazarlar: Christina eJanko, Sandra eFranz, Luis E. Munoz, Stefan eSiebig, Silke eWinkler, Georg eSchett, Kirsten eLauber, Ahmed eSheriff, Johan eVan Der Vlag, Martin eHerrmann
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2011-12-01
Seri Bilgileri:Frontiers in Immunology
Konular:
Inflammation
immune complexes
SLE
anti-CRP
anti-dsDNA
Clearance
Online Erişim:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00070/full
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