Low-dose naltrexone extends healthspan and lifespan in C. elegans via SKN-1 activation

Summary: As the global aging population rises, finding effective interventions to improve aging health is crucial. Drug repurposing, utilizing existing drugs for new purposes, presents a promising strategy for rapid implementation. We explored naltrexone from the Library of Integrated Network-based...

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Prif Awduron:	Weisha Li, Rebecca L. McIntyre, Bauke V. Schomakers, Rashmi Kamble, Anne H.G. Luesink, Michel van Weeghel, Riekelt H. Houtkooper, Arwen W. Gao, Georges E. Janssens
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2024-06-01
Cyfres:	iScience
Pynciau:	Biological process Cellular physiology Molecular biology
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2589004224011714
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