PI 3 kinase related kinases-independent proteolysis of BRCA1 regulates Rad51 recruitment during genotoxic stress in human cells.

<h4>Background</h4>The function of BRCA1 in response to ionizing radiation, which directly generates DNA double strand breaks, has been extensively characterized. However previous investigations have produced conflicting data on mutagens that initially induce other classes of DNA adducts. Because of...

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Principais autores:	Ian Hammond-Martel, Helen Pak, Helen Yu, Raphael Rouget, Andrew A Horwitz, Jeffrey D Parvin, Elliot A Drobetsky, El Bachir Affar
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science (PLoS) 2010-11-01
סדרה:	PLoS ONE
גישה מקוונת:	https://doi.org/10.1371/journal.pone.0014027
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!