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Crebanine, an aporphine alkaloid, induces cancer cell apoptosis through PI3K-Akt pathway in glioblastoma multiforme

Glioblastoma multiforme (GBM) is one of the most prevalent and lethal primary central nervous system malignancies. GBM is notorious for its high rates of recurrence and therapy resistance and the PI3K/Akt pathway plays a pivotal role in its malignant behavior. Crebanine (CB), an alkaloid capable of...

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書誌詳細
主要な著者: Poh-Shiow Yeh, Chien-Te Liu, Chia-Ying Yu, Ya-Chuan Chang, Shu-Yu Lin, Yun-Chen Li, Yu-Ze Luan, Wen-Wei Sung
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2024-06-01
シリーズ:Frontiers in Pharmacology
主題:
オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fphar.2024.1419044/full
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