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Novel Non-Congeneric Derivatives of the Choline Kinase Alpha Inhibitor ICL-CCIC-0019

Choline kinase alpha (CHKA) is a promising target for the development of cancer therapeutics. We have previously reported ICL-CCIC-0019, a potent CHKA inhibitor with high cellular activity but with some unfavorable pharmacological properties. In this work, we present an active analogue of ICL-CCIC-0...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ning Wang, Diana Brickute, Marta Braga, Chris Barnes, Haonan Lu, Louis Allott, Eric O. Aboagye
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2021-07-01
Rangatū:Pharmaceutics
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1999-4923/13/7/1078
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