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Development of bone seeker–functionalised microspheres as a targeted local antibiotic delivery system for bone infections

Objective: Bone infections are challenging to treat because of limited capability of systemic antibiotics to accumulate at the bone site. To enhance therapeutic action, systemic treatments are commonly combined with local antibiotic-loaded materials. Nevertheless, available drug carriers have undesi...

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Principais autores: Stijn G. Rotman, Keith Thompson, Dirk W. Grijpma, Robert G. Richards, Thomas F. Moriarty, David Eglin, Olivier Guillaume
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020-03-01
Series:Journal of Orthopaedic Translation
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2214031X19301895
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