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Expansion of influenza A(H1N1)pdm09 NA:S247N viruses with reduced susceptibility to oseltamivir, Catalonia, Spain, and in Europe, July to October 2025

Between July and October 2025, among the total 117 influenza A(H1N1)pdm09 strains characterised in Catalonia, 20% to 100% per week were carrying the NA:S247N substitution. The mutation, conferring reduced susceptibility to oseltamivir, was phenotypically confirmed (IC50 between 0.82 and 1.63 nM, com...

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Hovedforfatter: on behalf of the SIVIC Infectious diseases sentinel network
Format: Artigo
Sprog:Inglês
Udgivet: European Centre for Disease Prevention and Control 2025-12-01
Serier:Eurosurveillance
Fag:
A(H1N1)pdm09
S247N
Spain
oseltamivir
Catalonia
influenza
Online adgang:https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.48.2500873
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