A comprehensive appraisal of mechanism of anti-CRISPR proteins: an advanced genome editor to amend the CRISPR gene editing

The development of precise and controlled CRISPR-Cas tools has been made possible by the discovery of protein inhibitors of CRISPR-Cas systems, called anti-CRISPRs (Acrs). The Acr protein has the ability to control off-targeted mutations and impede Cas protein–editing operations. Acr can help with s...

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Principais autores:	Nisha Choudhary, Dipty Tandi, Rakesh Kumar Verma, Virendra Kumar Yadav, Naveen Dhingra, Tathagata Ghosh, Mahima Choudhary, Rajarshi K. Gaur, Magda H. Abdellatif, Amel Gacem, Lienda Bashier Eltayeb, Mohammed S. Alqahtani, Krishna Kumar Yadav, Byong-Hun Jeon
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-06-01
coleção:	Frontiers in Plant Science
Assuntos:	anti-CRISPR genome editing Acr inhibitors genetic memory CRISPR-Cas complex DNA binding inhibition
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fpls.2023.1164461/full
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