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Molecular evolution of aspartic protease gene family in vertebrates

Abstract Aspartic proteases are a gene superfamily with diverse functions in vertebrates, including pepsinogens (Pgs), the precursors of the major gastric enzyme pepsin. Despite their physiological importance, the evolutionary history of this gene family has been studied only in a fragmented manner....

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Bibliographic Details
Main Authors: Tatsuki Nagasawa, Tomofumi Inokuchi
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2026-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-026-52723-0
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