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Epigenetic control of gene function in schistosomes: a source of therapeutic targets?

The discovery of the epigenetic regulation of gene expression has revolutionized both our understanding of how genomes function and approaches to the therapy of numerous pathologies. Schistosomes are metazoan parasites and as such utilize most, if not all the epigenetic mechanisms in play in their v...

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Principais autores: Raymond John Pierce, Alejandro eCabezas-Cruz, Julien eLancelot, Stéphanie eCaby, Guilherme Corrêa De Oliveira
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014-09-01
Serier:Frontiers in Genetics
Fag:
DNA Methylation
Drug Discovery
MicroRNAs
epigenetics
histone modifying enzymes
Schistosome
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00317/full
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