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Two adjacent nuclear factor-binding domains activate expression from the human <it>PRNP </it>promoter

<p>Abstract</p> <p>Background</p> <p>The transmissible spongiform encephalopathies (TSEs) comprise a group of fatal degenerative neurological diseases in humans and other mammals. After infection, the cellular prion protein isoform PrP<sup>C </sup>is converted to the pathological PrP<sup>SC </sup>sc...

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Autori principali: Vostrov Alexander A, Izkhakov Nerik, Taheny Michael J, Quitschke Wolfgang W
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2009-09-01
Serie:BMC Research Notes
Accesso online:http://www.biomedcentral.com/1756-0500/2/178
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