Downregulation of IRF7-mediated type-I interferon response by LmCen –/– parasites is necessary for protective immunity
Abstract Leishmaniasis is a tropical disease caused by Leishmania parasites and currently has no licensed vaccines. We developed a dermotropic Leishmania major centrin gene-deleted strain (LmCen –/–) as a live attenuated vaccine. Recent studies have shown that type I interferons (IFNs) play importan...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Nature Portfolio
2024-12-01
|
| মালা: | npj Vaccines |
| অনলাইন ব্যবহার করুন: | https://doi.org/10.1038/s41541-024-01032-6 |
| ট্যাগগুলো: |
কোনো ট্যাগ নেই, প্রথমজন হিসাবে ট্যাগ করুন!
|