Human-Induced Pluripotent Stem Cell Models for Amyloid Cardiomyopathy: From Mechanistic Insights to Therapeutic Discovery

Amyloid cardiomyopathy (ACM), driven by transthyretin (TTR) and immunoglobulin light chain (LC) amyloid fibrils, remains a major clinical challenge due to limited mechanistic understanding and insufficient preclinical models. Human-induced pluripotent stem cells (iPSCs) have emerged as a transformat...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yufeng Liu, Muhammad Riaz
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2025-11-01
Цуврал:	Journal of Cardiovascular Development and Disease
Нөхцлүүд:	amyloid cardiomyopathy transthyretin amyloidosis light chain amyloidosis induced pluripotent stem cell-derived cardiomyocytes induced pluripotent stem cell-derived hepatocytes 3D tissue engineering
Онлайн хандалт:	https://www.mdpi.com/2308-3425/12/11/434
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!