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Genome wide exploration of the methylome in aggressive B-cell lymphoma in Golden Retrievers reveals a conserved hypermethylome

Few recurrent DNA mutations are seen in aggressive canine B cell lymphomas (cBCL), suggesting other frequent drivers. The methylated island recovery assay (MIRA-seq) or methylated CpG-binding domain sequencing (MBD-seq) was used to define the genome-wide methylation profiles in aggressive cBCL in Go...

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Principais autores: Shirley Chu, Anne Avery, Janna Yoshimoto, Jeffrey N. Bryan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2022-12-01
coleção:Epigenetics
Assuntos:
bcl
dlbcl
lymphoma
methylome
mira
sequencing
golden retriever
canine
cancer
Acesso em linha:http://dx.doi.org/10.1080/15592294.2022.2105033
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