A Genome-Wide CRISPR Interference Screen Reveals an StkP-Mediated Connection between Cell Wall Integrity and Competence in Streptococcus salivarius

ABSTRACT Competence is one of the most efficient bacterial evolutionary and adaptative strategies by synchronizing production of antibacterial compounds and integration of DNA released by dead cells. In most streptococci, this tactic is orchestrated by the ComRS system, a pheromone communication dev...

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Principais autores:	Adrien Knoops, Alexandra Waegemans, Morgane Lamontagne, Baptiste Decat, Johann Mignolet, Jan-Willem Veening, Pascal Hols
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2022-12-01
Series:	mSystems
Assuntos:	cell-to-cell communication genome-wide screen quorum sensing DNA transformation ComRS cell wall
Acceso en liña:	https://journals.asm.org/doi/10.1128/msystems.00735-22
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